Yes absolutely. You could set the Amp and ceiling speakers as surround speakers to the Arc if the ceiling speakers are suitably positioned. That would appear as a single ‘room’ in Sonos and would sync perfectly for TV and music.
Alternatively you could set up the Amp and Arc as separate ‘rooms’, and associate the Sub with whichever you choose - Amp or Arc. You can play one or other or both independently in this set up. When grouped they will sync perfectly for music but not for TV - there will be an echo effect.
You can switch the AMP from surround mode to standalone mode (provided Sub is associated with the Arc) but it is a bit of faff, especially if you Trueplay tune each time.