Could you please explain what you mean by 2no and 4no?

 @RobElec You can use two Sonos Amps and four in-ceiling speakers for a home theater setup. One Amp will power the left front and right front speakers, and one Amp will power the two surround speakers. This will give you a 4.0 home theater setup with a phantom center channel. You can add a Sonos Sub to make it a 4.1 setup.

FYI… using in-ceiling speakers for the two front channels is usually not recommended for a home theater setup. The better option would be to get a Sonos sound bar like an Arc or Beam for the front/center channels and then add the Amp/in-ceiling speakers as surrounds.