Play 5 (pair) EQ Bass Setting vs. Sub Bass Setting

Apologies if this has already been covered. I've just paired a new Sub with a pair of Play 5s (perhaps overkill, but loving it). Can someone please give me an overview of the difference between increasing the bass in the Play 5 EQ setting and boosting the Sub's bass directly? Does the former action only affect the Play 5, or does it boost the Sub's bass as well? Is there a crossover setting I am not seeing? Should I use the two levers in conjunction with each other? I understand the "musical taste" theory, so I'm just looking for some technical help and maybe everyone's experiences with adjusting the two levers. Thanks.
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