The only way to use WiSA with your B&O speakers would be to add a Sonos Port to your system, connected to a B&O “Transmitter 1”. Cabling the speakers to the Sonos Port analog output will almost always work better. But yes, please do say which speakers...
(In advance of your answer, some speculation: Presumably you are using WiSA with a B&O television now, else you would know of (already have purchased) the Transmitter-1? Given the potential for interference between WiSA and 5GHz Wi-Fi, you might want to avoid doing Sonos surrounds or sub with their TV speakers like the Arc or Beam -- which uses the unlicensed 5GHz band for its own communications. To avoid the silent delay while the Transmitter 1 establishes a connection with the speakers each time, there is a way to set it to “always on”, which your B&O dealer should do for free if you decide you need it after install. Before or after getting advice here, ask your favorite internet search engine “site:beoworld.org sonos wisa delay”.)