Yes. But Sonos advises the (bigger) Sub.

 Two of them!

I’m aware the above comment relates to the previous comment, rather than the original post, but to avoid any potential confusion for others, you can’t add 2 Sub Minis to the Arc/Arc Ultra, only one.

I’d suggest the full Sub too, the mini seems better matched to 100s or the Beam/Ray than the Arc.

If considering two pay careful attention to which generation Sub you are getting as not all will work together.

Thanks for the info,  I have a smaller space so I didn’t think I needed the full size.

I have a full Sub in a 10x10 foot room with a Beam and it works well, a Mini might have worked there too. Much larger and I would be concerned with matching the Arc's output levels at higher volume levels 

Describe your space and see what others think