Sonos Boost exacerbated speaker dropout issues

I have a fairly modest Sonos setup: two Five’s in a pair with a Sub in the living room, and two One’s in a pair in the bedroom. I started experiencing dropout issues when I added the Sub. What will happen is the right Five (it’s always the right) and the Sub will start playing at the beginning of a song and almost immediately drop out. They eventually come back after about ten seconds. The left side never drops out. This would only happen when playing from a service such as Qobuz or Amazon HD. I spoke with tech support and we came to the conclusion that a Boost would help remedy the issue. I received my Boost today, plugged it in, and now the issue happens much more frequently, and on every service (Spotify specifically, where it was not happening before). My network matrix shows all green, except for the Boost itself. What is most frustrating is that, as I stated previously, none of these issues were present before I purchased the Sub. This has made using Sonos almost a chore, and caused me to seriously second guess my decision to buy into the ecosystem. 

There is roughly a five foot hop from the Boost to the left Five, and the two One’s are in an adjacent room. I have no other networking issues in the house aside from my Sonos system. 

Airplay 2 works fine. There are zero issues when streaming from an iOS or MacOS device.