Multi-room is what Sonos is great at. Just use the “group” feature for synchronised multi-room play (unless your source is tv via your Arc - other rooms will then have an unavoidable 70msec delay).

To optimise music quality, go for stereo-paired Fives, maybe with Sub, and stream high-definition audio. Or use a turntable with pre-amp and input through the Five’s line-in. 
 

As said, multi-room just works. The Group function lets you pick any set of rooms or all and they just play.

The turntable, or other line-level source is good too. We used to use a multi-CD changer to avoid having to flip CDs too often.

Folks here helped mt rip my CD collection to a local NAS and I never looked back. I followed the advice to rip to a lossless format (FLAC here) so I lost no quality from the original CD version. Now I can just click a song or album to play or add multiples to the queue. Last week I donated my CD cabinet and moved all the CDs to storage (have to keep them for copyright issues) and never intend to see them again.

I’m a big Five fan, a Sub is nice too as it really fills out the low end but with the Fives it isn’t essential. 

The 300s are seeing good reports, I don’t have them, but a Sub or mini-Sub seems to be recommended.

Smaller the 100s and a mini-Sub are a nice paring.

I’m also an Arc fan, while I have several Beams, the Arc shines in my larger space. The Beams are not bad in smaller ones or for watching TV shows. Adding a Sub or even mini-Sub helps both, you can go hog-wild with two Subs too but expect spousal push-back when you shake the windows.

100s or better 300s for surrounds will add a lot to movie watching, the 300s are reported to give even better Atmos sound and are worth the additional cost if you use it.

If you have a supported Apple device you can also run the Sonos Trueplay speaker tuning system. Some rooms it really helps, some show little difference and a few seem to sound worse. No worries there as it is easy to toggle on/off and pick the best sound.