I have most of my speakers ‘wired’, and my Roam is on my WiFi, with no issues at all, even when grouping rooms. 

I’d be looking at two things to address ‘responsiveness’. First, and most common is wifi interference. Second, less likely, but possible in either wired or wireless systems, is duplicate IP addresses. A quick network refresh, of unplugging the Sonos devices, rebooting the router, then plugging back in the Sonos devices would likely help that, althoipugh setting up reserved IP addresses in the router is a more ‘permanent’ way of doing the same thing. But if both of those don’t rectify the responsiveness issue, I would recommend that you submit a system diagnostic within 10 minutes of experiencing this problem, and call Sonos Support to discuss it.

There may be information included in the diagnostic that will help Sonos pinpoint the issue and help you find a solution.

When you speak directly to the Support staff, they have tools at their disposal that will allow them to give you advice specific to your network and Sonos system.

Remember, if you wire one or more Sonosnet compatible Sonos devices all Sonosnet Compatible Sonos will ignore your WiFi and attempt to connect to Sonosnet.

I’m in that situation now and I was planning to swap to an all WiFi setup when the new app glitches hit and I decided to wait it out. I don’t have any of the WiFi only devices so I can have no mixed-mode issues.

I will be going WiFi only at some point, it seems to be the direction Sonos is heading.

 Do you have EERO satellites on each floor?  Would it be possible to Ethernet backhaul where the satellites are connected to each other?  Then run all Sonos wireless.

I would try wiring as many units as possible. If performance suffers, you can go back by simply unwiring. If the partially wired setup is balky, power down PLAY:3 as a test. I have no proof, but I suspect that PLAY:3 is sometimes starved for memory and gets into trouble. Also, avoid using PLAY:3 as the first member when building a Group.

Ok.  So I ended up moving more of my eero satellites to wired first.  
 

Then I wired a handful of my Sonos gear.  4 of my 9 zones.  And disabled WiFi on them.  
 

Wow, it completely eliminated all lag.   Seems like a major improvement so far.  
 

i was worried reading about how that changes everything to SonosNet.   Or if new problems would crop up.  So far all good.  I'm upset I didn't do this earlier. 
 

Besides being wired.  I also think the reduction in wireless signal in my house probably is helping with some interference issues i may have been having. 
 

Keep in mind the disable WiFi doesn’t just do that, it disables the whole radio which is used for surrounds too.

Yes, that was my worry. And my subs and surrounds initially turned off.  But after about 3 minutes they came back up. 
 

Ok, I spoke too soon. 
I started to hear some subtle skipping on my back surrounds off of my beam.  :(

I called Sonos and submitted a diagnostic.  They agreed that hooking up Ethernet was a good thing but for any home theatre setups or zones that use a sub, I should keep WiFi enabled.  
 

• note: my next challenge is ensuring that music doesn't go out because we are using the same Spotify account in multiple zones or in the car at the same time.  Normally not a big deal but when we have parties I've been known to scramble trying to figure out why that was happening.   Now that my network is stable, I've gained confidence that that is my next battle to protect against. 

For parties using your Sonos Music Library gives you fewer things to go wrong.

If you get skipping from too many bodies in the room with lossless transcode to lossy MP3 and see if that helps.