No.  One source at a time only.

The Amp will allow you to GROUP a line-in source CD or TT audio to other Sonos speakers. If the Amp is your only Sonos product you are then connecting it to wired or line-in powered speakers to hear audio that is STREAMED to it or used as a grouped Sonos product to capture audio being Streamed to another Sonos speaker. Or you may be using it as receiver of HDMI input from a TV to send audio to wired speakers. You can also use the Amp in a home theater setup with a Sonos Sounbar to power wired speakers used as surrounds. To conclude the answer is no to your question.

I’m not sure what you are asking. It is possible to play an online music service through AMP, while playing an analog source connected to AMP’s Line-In through another player or Group of players.