I currently have two Play:5 in a Loft\LR\Sanctuary overlooking my MBR. In the MBR I have a Sonos One. I generally play music on both the Sonos One and the Play:5s at the same time.
I am thinking of adding a Sub to either the Play:5s in the Loft or the Sonos One in the MBR and adding another Sonos One.
I currently have a Sub in a 5.1 Surround in the Media Room and it is awesome. I generally use more for music since I am not a huge TV fan. I am afraid I maybe addicted to these speakers and maybe going a tad overboard.